Laboratory of Physical and Chemical Methods for Structure Analysis at the Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences was founded in 2002. The laboratory’s research activities are focussed on the liquid chromatography and mass spectrometry instrumentation and method developments for the analysis of peptides and proteins. The on-going projects in the laboratory are mostly in the field of proteomics and bioinformatics. Laboratory’s experimental infrastructure includes:
- Quadrupole radiofrequency ion trap mass spectrometer Amazon SL (Bruker Daltonics) coupled to nano-flow HPLC system Ultimate 3000 nanoRSLC (Dionex/ThermoFisher Scientific);
- A hybrid 1.25T permanent magnet benchtop ion cyclotron resonance mass spectrometer FTICR/MS with ESI/DESI/DART ionization sources and coupled to a gradient HPLC system Dynamax SD-200 (Reinin/Varian Inc.);
- Gradient HPLC system Gilson 305/306.
In addition to the major HPLC/MS equipment the Laboratory has a variety of sample preparation tools such as centrifuges, shakers, analytical balances, pH-meter, ultrasonic bath, etc., as well as different kinds of devices for measuring and processing electric signals.
The Laboratory is involved into the undergraduate and graduate programs at Moscow Institute of Physics and Technology (State University), Department of Molecular and Biological Physics. Students from all levels of these programs are the main part of the members of the Laboratory.